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Publication Detail
Suitability of commercial colloids for magnetic hyperthermia
  • Publication Type:
    Conference
  • Authors:
    Kallumadil M, Tada M, Nakagawa T, Abe M, Southern P, Pankhurst QA
  • Publisher:
    ELSEVIER SCIENCE BV
  • Publication date:
    05/2009
  • Pagination:
    1509, 1513
  • Published proceedings:
    JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
  • Volume:
    321
  • Issue:
    10
  • Name of conference:
    7th International Conference on Scientific and Clinical Applications of Magnetic Carriers
  • Conference place:
    Vancouver, CANADA
  • Conference start date:
    20/05/2008
  • Conference finish date:
    24/05/2008
  • Print ISSN:
    0304-8853
  • Language:
    EN
  • Keywords:
    Magnetic hyperthermia, Ferrofluid, Iron oxide, Commercial colloids, Intrinsic loss power, Specific absorption rate, Specific loss power, Maghemite, Magnetite, Ferrous, Ferric, Crystallite diameter, Cancer, NANOPARTICLES, FIELD
  • Addresses:
    Kallumadil, M
    Royal Inst Great Britain
    Davy Faraday Res Lab
    London
    W1S 4BS
    England

    UCL
    London Ctr Nanotechnol
    London
    WC1 H 0AH
    England
Abstract
Commercial nanoparticles supplied by Chemicell, Micromod and Bayer-Schering were characterised with regard to their nanocrystalline diameter, hydrodynamic diameter, total iron content and relative ferrous iron content. Additionally, calorimetric measurements were taken using a 900 kHz AC magnetic field of amplitude 5.66 kA/m. It was found that those samples containing relatively high (> 18%) ferrous content generated a substantially smaller (12% on average) intrinsic loss power (ILP) than those samples with a lower ferrous content. Two nominally identical Chemicell samples that differed only in their production date showed significantly different ILPs, attributed to a variation in batch-to-batch crystallite sizes. The highest ILP values in the cohort, ca. 3.1 nHm(2)/kg, were achieved for particles with hydrodynamic diameters of ca. 70nm and nanocrystalline diameters of ca. 12 nm. These compare favourably with most samples prepared in academic laboratories, although they are not as high as the ca. 23.4nHm(2)/kg reported for naturally occurring bacterial magnetosomes. (c) 2009 Elsevier B.V. All rights reserved.
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