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Publication Detail
A therapeutic trial of milacemide in myoclonus and the stiff-person syndrome.
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Journal Article
  • Authors:
    Brown P, Thompson PD, Rothwell JC, Day BL, Marsden CD
  • Publication date:
    1991
  • Pagination:
    73, 75
  • Journal:
    Mov Disord
  • Volume:
    6
  • Issue:
    1
  • Status:
    Published
  • Country:
    United States
  • Print ISSN:
    0885-3185
  • Language:
    eng
  • Keywords:
    Acetamides, Adult, Aged, Anticonvulsants, Female, Humans, Male, Middle Aged, Monoamine Oxidase Inhibitors, Muscle Rigidity, Myoclonus, Neurologic Examination, Spasm, Syndrome
Abstract
We investigated the therapeutic effects of milacemide in seven patients with myoclonus and three patients with the stiff-person syndrome in an open-label trial. Milacemide was initiated at 800 mg/day and was gradually increased to a maximum dosage of 2,400 mg/day. No significant improvement occurred in the 10 patients.
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