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Publication Detail
Reciprocal inhibition between forearm muscles in patients with writer's cramp and other occupational cramps, symptomatic hemidystonia and hemiparesis due to stroke.
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Comparative Study
  • Authors:
    Nakashima K, Rothwell JC, Day BL, Thompson PD, Shannon K, Marsden CD
  • Publication date:
  • Pagination:
    681, 697
  • Journal:
  • Volume:
    112 ( Pt 3)
  • Status:
  • Country:
  • Print ISSN:
  • Language:
  • Keywords:
    Adolescent, Adult, Aged, Cerebrovascular Disorders, Dystonia, Female, Forearm, H-Reflex, Hemiplegia, Humans, Male, Middle Aged, Muscle Cramp, Muscle Spasticity, Muscle Tonus, Muscles, Occupational Diseases, Reflex, Monosynaptic, Writing
Reciprocal inhibition of H reflexes in the forearm flexor muscles was examined in a group of 16 patients with writer's and other occupational cramps. The early disynaptic phase of reciprocal inhibition was normal. However, there was a reduction in the amount of later, presynaptic inhibition, when compared with age-matched normal subjects. Similar findings were seen in 2 patients with symptomatic hemidystonia in whom structural brain lesions were present. However, this reduction in presynaptic inhibition was not specific to patients with dystonia. In a further group of 13 patients with hemiparesis or hemiplegia due to stroke, abnormalities of both early and later phases of reciprocal inhibition were found. The patients with spasticity exhibited less disynaptic inhibition than those with normal tone or flaccid limbs. The changes in the presynaptic phase of reciprocal inhibition did not correlate with the clinical signs of spasticity and increased muscle tone. These results provide objective evidence of a physiological basis for the action or task-specific focal dystonias such as writer's cramp.
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