UCL  IRIS
Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
Publication Detail
The movement-related cortical potential is abnormal in patients with idiopathic torsion dystonia.
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Comparative Study
  • Authors:
    Van der Kamp W, Rothwell JC, Thompson PD, Day BL, Marsden CD
  • Publication date:
    09/1995
  • Pagination:
    630, 633
  • Journal:
    Mov Disord
  • Volume:
    10
  • Issue:
    5
  • Status:
    Published
  • Country:
    United States
  • Print ISSN:
    0885-3185
  • Language:
    eng
  • Keywords:
    Adult, Aged, Basal Ganglia, Dystonia Musculorum Deformans, Electric Stimulation, Electromyography, Evoked Potentials, Motor, Humans, Middle Aged, Motor Cortex, Movement Disorders
Abstract
Voluntary movements, such as the self-paced finger extension task used in the present experiments, are preceded by a slowly rising negative electroencephalographic potential [the movement-related cortical potential (MRCP)]. The early NS1 component of the potential was no different in patients with primary dystonia affecting the arm (n = 6) compared with matched controls. In contrast, the peak amplitude of the MRCP was smaller in the patients, despite the fact that the movements made by the two groups were very similar; it was of equal size over both left and right hemispheres, rather than being larger on the side contralateral to the movement. These results are similar to those observed by others in patients with symptomatic dystonia secondary to lesions of the basal ganglia or their output pathways and may reflect abnormal basal ganglia input to motor areas of cortex before the onset of a self-paced movement.
Publication data is maintained in RPS. Visit https://rps.ucl.ac.uk
 More search options
UCL Researchers
Author
UCL Queen Square Institute of Neurology
Author
Clinical and Movement Neurosciences
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by