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Publication Detail
Comparison and evaluation of rigid, affine, and nonrigid registration of breast MR images
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Journal Article
  • Authors:
    Denton ERE, Sonoda LI, Rueckert D, Rankin SC, Hayes C, Leach MO, Hill DLG, Hawkes DJ
  • Publication date:
  • Pagination:
    800, 805
  • Journal:
    Journal of Computer Assisted Tomography
  • Volume:
  • Issue:
  • Status:
  • Print ISSN:
Purpose: A new nonrigid registration method, designed to reduce the effect of movement artifact in subtraction images from breast MR, is compared with existing rigid and affine registration methods. Method: Nonrigid registration was compared with rigid and affine registration methods and unregistered images using 54 gadolinium-enhanced 3D breast MR data sets. Twenty-seven data sets had been previously reported normal, and 27 contained a histologically proven carcinoma. The comparison was based on visual assessment and ranking by two radiologists. Results: When analyzed by two radiologists independently, all three registration methods gave better- quality subtraction images than unregistered images (p < 0.01), but nonrigid registration gave significantly better results than the rigid and affine registration methods (p < 0.01). There was no significant difference between rigid and affine registration methods. Conclusion: Nonrigid registration significantly reduces the effects of movement artifact in subtracted contrast-enhanced breast MRI. This may enable better visualization of small tumors and those within a glandular breast.
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