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Publication Detail
Structured illumination and time gated detection for diffuse optical imaging
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  • Authors:
    D'Andrea C, Bassi A, Valentini G, Cubeddu R, Arridge S
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  • Published proceedings:
    Progress in Biomedical Optics and Imaging - Proceedings of SPIE
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Temporal propagation of sinusoidally modulated light in in-homogeneous diffusive samples is investigated experimentally and by finite element simulations, showing that the amplitude and the phase of the sinusoid are affected by the presence of inclusions. Enhancement of imaging resolution with high spatial frequencies and early time-gating is shown. Detection of the phase of the modulated light is proposed as a new method for the accurate localization of tissue in-homogeneities. A fast 3-dimensional reconstruction based on the detection of spatially modulated light at a limited number of spatial frequencies is discussed. © 2009 SPIE-OSA.
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