UCL  IRIS
Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
Publication Detail
Preliminary evidence for gut involvement in the pathogenesis of rheumatoid arthritis?
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Journal Article
  • Authors:
    Segal AW, Isenberg DA, Hajirousou V, Tolfree S, Clark J, Snaith ML
  • Publication date:
    05/1986
  • Pagination:
    162, 166
  • Journal:
    Br J Rheumatol
  • Volume:
    25
  • Issue:
    2
  • Status:
    Published
  • Country:
    England
  • Print ISSN:
    0263-7103
  • Language:
    eng
  • Keywords:
    Adult, Aged, Anti-Inflammatory Agents, Arthritis, Rheumatoid, Female, Humans, Indium, Intestines, Leukocytes, Male, Middle Aged, Organometallic Compounds, Oxyquinoline, Permeability, Radioisotopes
Abstract
111Indium leucocyte scans were performed on 26 patients with active rheumatoid arthritis. An abnormal localization of radioactivity was observed in the gut of 12 of these patients, generally in the region of the terminal ileum, caecum and ascending colon. No difference was found in the intake of nonsteroidal anti-inflammatory drugs between those with positive and negative scans. Two patients with positive scans were on no medication. These observations suggest the possibility of a primary role for a gastrointestinal lesion in the aetiology of rheumatoid arthritis, although these abnormalities could be secondary or unrelated.
Publication data is maintained in RPS. Visit https://rps.ucl.ac.uk
 More search options
UCL Researchers
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by