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Publication Detail
Capturing Complex Enhancer Regulatory Hubs? Try Tri-C.
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Publication Type:Journal article
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Publication Sub Type:Article
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Authors:Varsally W, Hadjur S
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Publication date:03/12/2018
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Pagination:543, 544
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Journal:Dev Cell
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Volume:47
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Issue:5
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Status:Published
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Country:United States
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PII:S1534-5807(18)30977-8
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Language:eng
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Author URL:
Abstract
A recent study in Nature Genetics (Oudelaar et al., 2018) has developed a new method to study multi-way chromatin interactions at the allelic level from regulatory elements with high sensitivity and resolution. The method, termed 'Tri-C' is used to explore the combinatorial interactions between multiple regulatory elements underlying precise gene regulation of the globin locus.
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