UCL  IRIS
Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at http://www.ucl.ac.uk/finance/research/post_award/post_award_contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
Publication Detail
Detecting and comparing the onset of myocardial activation and regional motion changes in tagged MR for XMR-guided RF ablation
  • Publication Type:
    Conference
  • Authors:
    Sanchez-Ortiz GI, Sermesant M, Rhode KS, Chandrashekara R, Razavi R, Hill DLG, Rueckert D
  • Publication date:
    27/09/2005
  • Pagination:
    348, 358
  • Published proceedings:
    Lecture Notes in Computer Science
  • Volume:
    3504
  • Status:
    Published
  • Print ISSN:
    0302-9743
Abstract
Radio-frequency (RF) ablation uses electrode-catheters to destroy abnormally conducting myocardial areas that lead to potentially lethal tachyarrhythmias. The procedure is normally guided with x-rays (2D), leading to errors in location and excessive radiation exposure. One of our goals is to provide pre- and intra-operative 3D MR guidance in XMR systems (combined X-ray and MRI room) by locating myocardial regions with abnormal electrical conduction patterns. We address the inverse electro-mechanical relation by using motion in order to infer electrical propagation. For this purpose we define a probabilistic measure of the onset of regional myocardial activation derived from motion fields. The 3D motion fields are obtained using non-rigid registration of tagged MR sequences to track the heart. The myocardium is subdivided in segments and the derived activation isochrones maps compared. We also compare regional motion between two different image acquisitions, thus assisting in diagnosing arrhythmia, in follow up of treatment, and particularly in determining whether the electro-physiological intervention succeeded. We validate our methods using an electro-mechanical model of the heart, synthetic data from a cardiac motion simulator for tagged MRI, a cardiac MRI atlas of motion and geometry, MRI data from 6 healthy volunteers (one of them subjected to stress), and an MRI study on one patient with tachyarrhythmia, before and after RF ablation. Results seem to corroborate that the ablation had the desired effect of regularising cardiac contraction. © Springer-Verlag Berlin Heidelberg 2005.
Publication data is maintained in RPS. Visit https://rps.ucl.ac.uk
 More search options
UCL Researchers
Author
Dept of Med Phys & Biomedical Eng
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by