Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
Publication Detail
Early onset cerebral amyloid angiopathy following childhood exposure to cadaveric dura
  • Publication Type:
    Journal article
  • Publication Sub Type:
  • Authors:
    Banerjee G, Adams ME, Jaunmuktane Z, Lammie GA, Turner B, Wani M, Sawhney IMS, Houlden H, Mead S, Brandner S, Werring DJ
  • Publisher:
  • Publication date:
  • Journal:
    Annals of Neurology
  • Status:
    Published online
  • Country:
    United States
  • Print ISSN:
  • Language:
  • Keywords:
    Amyloid-beta, Cerebral amyloid angiopathy, Prion
Amyloid-β transmission has been described in patients both with and without iatrogenic Creutzfeldt-Jakob disease; however, there is little information regarding the impact of this acquired amyloid-β pathology during life. Here, for the first time, we describe in detail the clinical and neuroimaging findings in three patients with early-onset symptomatic amyloid-β cerebral amyloid angiopathy following childhood exposure to cadaveric dura (by neurosurgical grafting in two patients, and tumour embolization in a third). Our observations provide further in vivo evidence that cerebral amyloid angiopathy might be caused by transmission of amyloid-β seeds (prions) present in cadaveric dura, and has diagnostic relevance for younger patients presenting with suspected cerebral amyloid angiopathy. This article is protected by copyright. All rights reserved.
Publication data is maintained in RPS. Visit https://rps.ucl.ac.uk
 More search options
UCL Researchers Show More
UCL Institute of Prion Diseases
Neurodegenerative Diseases
Department of Neuromuscular Diseases
Clinical and Movement Neurosciences
MRC Prion Unit at UCL
Brain Repair & Rehabilitation
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by