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Publication Detail
Cytoskeletal Control of Antigen-Dependent T Cell Activation
  • Publication Type:
    Journal article
  • Publication Sub Type:
  • Authors:
    Colin-York H, Javanmardi Y, Skamrahl M, Kumari S, Chang VT, Khuon S, Taylor A, Chew TL, Betzig E, Moeendarbary E, Cerundolo V, Eggeling C, Fritzsche M
  • Publication date:
  • Journal:
    Cell Reports
  • Status:
© 2019 The Author(s) T cell activation relies on a dynamic actin cytoskeleton. Here, Colin-York et al. show how the kinetics of the stimulating antigen influence the dynamics of actin. This feedback mechanism influences the mechanics at the immune synapse, allowing T cells to orchestrate the length scale and timescale of signaling.
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