UCL  IRIS
Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
Publication Detail
Elevated levels of the 90 kd heat shock protein in patients with systemic lupus erythematosus are dependent upon enhanced transcription of the hsp90β gene
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Journal Article
  • Authors:
    Twomey BM, Dhillon VB, McCallum S, Isenberg DA, Latchman DS
  • Publication date:
    01/01/1993
  • Pagination:
    495, 506
  • Journal:
    Journal of Autoimmunity
  • Volume:
    6
  • Issue:
    4
  • Status:
    Published
  • Print ISSN:
    0896-8411
Abstract
The level of the 90 kD heat shock protein (hsp90) has been shown to be elevated in the peripheral blood mononuclear cells of a subset of SLE patients. We show that this increased level of hsp90 is primarily dependent upon the enhanced transcription of the hsp90β gene which is observed in these patients but not in normal controls or SLE patients without elevated protein levels. Elevated transcription of the hsp90β gene in SLE patients is not in general paralleled by enhanced transcription of the hsp70 or ubiquitin genes indicating that the hsp90β gene is specifically activated in some SLE patients. © 1993 Academic Press Limited.
Publication data is maintained in RPS. Visit https://rps.ucl.ac.uk
 More search options
UCL Researchers
Author
ICH - Directors Office
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by