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Publication Detail
Elevation of the levels of SmB, B′ and D proteins but not that of the La (SS-B) antigen during HSV infections
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Journal Article
  • Authors:
    Sharpe NG, Isenberg D, Williams DG, Latchman DS
  • Publication date:
    01/01/1989
  • Pagination:
    701, 708
  • Journal:
    Journal of Autoimmunity
  • Volume:
    2
  • Issue:
    5
  • Status:
    Published
  • Print ISSN:
    0896-8411
Abstract
Three Sm proteins, B, B′ and D, which are highly immunoreactive in systemic lupus erythematosus (SLE), increase in abundance in Vero cells infected with laboratory strains and clinical isolates of herpes simplex virus (HSV) types 1 and 2. The autoimmune antigen La (SS-B) does not accumulate in identical infections. The significance of the Sm antigen accumulation is discussed in terms of its possible role in HSV infection and in connection with the origin of autoantibodies in SLE. © 1989 Academic Press Limited.
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