UCL  IRIS
Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
Publication Detail
Antinuclear antibodies, antibodies to DNA, histones, and nucleosomes
  • Publication Type:
    Chapter
  • Authors:
    Isenberg D, Giles I, Hansen JE, Rahman A
  • Publication date:
    01/01/2018
  • Pagination:
    355, 365
  • ISBN-13:
    9780323479271
  • Status:
    Published
  • Book title:
    Dubois' Lupus Erythematosus and Related Syndromes
Abstract
Antinuclear antibodies are present in high titers in over 95% of patients with systemic lupus erythematosus (SLE). The precise targets of these antibodies are, however, highly variable and include double-stranded (ds)DNA, histones, ribonucleoprotein (RNP), and Sm antigens. The presence of antinuclear antibodies (ANAs) is a criterion for SLE but these antibodies are not specific and may be found in healthy individuals (some, but not all, of whom will go on to develop lupus) and those with infections in whom the ANA is a transient phenomenon. Titers of ANA are of little use in reflecting disease activity in SLE.
Publication data is maintained in RPS. Visit https://rps.ucl.ac.uk
 More search options
UCL Researchers
Author
Inflammation
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by