UCL  IRIS
Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
Publication Detail
Welcoming back my arm: affective touch increases body ownership following right hemisphere stroke
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Article
  • Authors:
    Jenkinson PM, Papadaki C, Besharati S, Moro V, Gobbetto V, Crucianelli L, Kirsch LP, Avesani R, Ward NS, Fotopoulou A
  • Publisher:
    Oxford University Press (OUP)
  • Publication date:
    28/03/2020
  • Journal:
    Brain Communications
  • Status:
    Published
  • Language:
    en
Abstract
Abstract Right hemisphere stroke can impair the ability to recognise one’s contralesional body parts as belonging to one’s self. The study of this so-called ‘disturbed sense of limb ownership’ can provide unique insights into the neurocognitive mechanisms of body ownership. Here, we address a hypothesis built upon experimental studies on body ownership in healthy volunteers. These studies have shown that affective (pleasant) touch, an interoceptive modality associated with unmyelinated, slow-conducting C tactile afferents, has a unique role in the sense of body ownership. Here we systematically investigated whether affective touch stimulation could increase body ownership in patients with a disturbed sense of limb ownership following right hemisphere stroke. An initial feasibility study in 16 adult, acute stroke patients enabled us to optimise and calibrate an affective touch protocol to be administered by the bedside. The main experiment, conducted with a different sample of 26 right hemisphere patients, assessed changes in limb ownership elicited following self- (patient) versus other- (experimenter) generated tactile stimulation, using a velocity known to optimally activate C-tactile fibres (i.e. 3cm/s), and a second velocity that is suboptimal for C-tactile activation (i.e. 18cm/s). We further examined the specificity and mechanism of observed changes in limb ownership in secondary analyses looking at (1) the influence of perceived intensity and pleasantness of touch, (2) touch laterality, and (3) level of disturbed sense of limb ownership on ownership change, as well as (4) changes in unilateral neglect arising from touch. Findings indicated a significant increase in limb ownership following experimenter-administered, C-tactile-optimal touch. Voxel-based Lesion-Symptom Mapping identified damage to the right insula and, more substantially, the right corpus callosum, associated with a failure to increase body ownership following experimenter-administered, affective touch. Our findings suggest that affective touch can increase the sense of body-part ownership following right hemisphere stroke, potentially due to its unique role in the multisensory integration processes that underlie the sense of body ownership.
Publication data is maintained in RPS. Visit https://rps.ucl.ac.uk
 More search options
UCL Researchers
Author
Clinical, Edu & Hlth Psychology
Author
Clinical and Movement Neurosciences
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by