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Publication Detail
Application of Biomechanical Modelling to Image-Guided Breast Surgery
  • Publication Type:
  • Authors:
    Carter T, Han L, Taylor Z, Tanner C, Beechy-Newman N, Ourselin S, Hawkes D
  • Publication date:
  • Pagination:
    71, 94
  • Volume:
  • Status:
  • Book title:
    Studies in Mechanobiology, Tissue Engineering and Biomaterials
© 2012, Springer-Verlag Berlin Heidelberg. Patients who undergo breast-conserving surgery frequently require more than one operation as cancerous tissue may not be completely excised at the first attempt. Image-guidance which exploits the 3D information available in preoperative dynamic contrast enhanced (DCE) magnetic resonance (MR) images may help to reduce the re-excision rate. However, significant deformation of the soft tissue of the breast occurs between imaging and surgery because these DCE MR images must be acquired with the patient positioned prone, but surgery is performed supine. This limits the applicability of MR for guiding breast surgery. In this chapter we describe how a patient-specific biomechanical model, based on preoperative MR images, can assist in the task of locating the lesion in the operating theatre.
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