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Publication Detail
Lupus in the family--analysis of a cohort followed from 1978 to 1999
  • Publication Type:
    Journal article
  • Publication Sub Type:
  • Authors:
    Giles I, Isenberg D
  • Publication date:
  • Pagination:
    38, 44
  • Journal:
  • Volume:
  • Issue:
  • Print ISSN:
  • Keywords:
    adult, COHORT, Cohort Studies, COMMON, Daughter, DEVELOPED, disease, epidemiology, factors, Familial, Female, FOLLOW UP, Follow-up, Follow-Up Studies, genetics, IM, LA, long term follow up, LONG-TERM, Lupus, Lupus Erythematosus, Systemic, Male, MOTHERS, Patient, patients, Prevalence, RELATIVES, Rheumatology
  • Notes:
    UI - 21132999 LA - eng PT - Journal Article DA - 20010312 IS - 0961-2033 SB - IM CY - England
Familial lupus is recognised but rarely described in mother-daughter case pairs. We describe the prevalence of lupus occurring in the first degree relatives of a cohort of 300 lupus patients under long-term follow-up at a specialised lupus clinic. Three instances of mothers and their daughters who both developed the disease are described in detail to try and ascertain whether there are any particular clinical/serological/genetic factors in common which might explain the phenomenon
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