When undertaking fieldwork in a complex/sensitive environment such as a busy hospital ward, it is vital that the recording technique is robust (to cater for various eventualities), reliable (to accurately capture data) and repeatable (to share the data). It is therefore important to test and prepare protocols to maximize the effectiveness of the time available for any observations. Our poster demonstrates a real-time simulation built using the Unreal Engine 3D game platform and applied to our ‘Paths of Resistant Pathogens’ research study. This project aims to tackle issues of antimicrobial resistance (AMR) - such as superbugs - through a detailed architecturally-informed analysis of transmission risks inherent in hospital design. The simulation provides a number of benefits to assist with piloting optimal methodologies and protocols including: 1. Time-critical trialing of protocols 2. Assessing the accuracy of protocols 3. Training observers