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Publication Detail
Endurance of Short Pulse Width Thalamic Stimulation Efficacy in Intention Tremor.
  • Publication Type:
    Journal article
  • Publication Sub Type:
  • Authors:
    Wirth T, Dayal V, de Roquemaurel A, Ferreira F, Vijiaratnam N, Akram H, Zrinzo L, Foltynie T, Limousin P
  • Publication date:
  • Pagination:
    1, 6
  • Journal:
    Stereotact Funct Neurosurg
  • Status:
  • Country:
  • PII:
  • Language:
  • Keywords:
    Ataxia, Deep brain stimulation, Essential tremor, Short pulse width, Ventral intermediate nucleus
The benefit of short pulse width stimulation in patients suffering from essential tremor (ET) refractory to thalamic deep brain stimulation remains controversial. Here, we add to the minimal body of evidence available by reporting the effect of this type of stimulation in 3 patients with a persistent and severe intention tremor component despite iterative DBS setting adjustments. While a reduction in pulse width to 30 μs initially showed promise in these patients by improving tremor control and mitigating cerebellar side effects arguably by widening the therapeutic window, these benefits seemed to dissipate during early follow-up. Our experience supports the need for measuring longer-term outcomes when reporting the usefulness of this mode of stimulation in ET.
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Dept of Med Phys & Biomedical Eng
Clinical and Movement Neurosciences
Clinical and Movement Neurosciences
Clinical and Movement Neurosciences
UCL Queen Square Institute of Neurology
Clinical and Movement Neurosciences
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