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Publication Detail
Re-structuring lentiviral vectors to express genomic RNA via cap-dependent translation
Abstract
© 2020 The Authors Here we describe the design and validation of a novel lentivirus-based mRNA delivery platform for delivery of therapeutic sequences to cells and tissues in vivo and ex vivo. The platform technology has potential use in the transient expression of engineered nucleases and vaccine development.
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Maternal & Fetal Medicine
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Genetics & Genomic Medicine Dept
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Maternal & Fetal Medicine
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Genetics & Genomic Medicine Dept
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Maternal & Fetal Medicine
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