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Publication Detail
Quality of life and mental health of patients with vascular malformations in a single specialist center in the United Kingdom.
Abstract
OBJECTIVE: Patients with vascular malformations suffer from chronic debilitating symptoms that have been shown to contribute negatively to their quality of life (QoL) and mental health. Despite this, the current literature evaluating the QoL and mental health of patients with vascular malformations remains scarce. The aim was to evaluate the QoL and mental health of patients with vascular malformations. METHODS: We prospectively analyzed the validated health-related QoL (HRQoL) questionnaires; RAND Health Care 36-Item Short Form Survey (SF-36), hospital anxiety and depression scale (HADS), and visual analogue score for pain (VAS-P) reported by 253 patients with vascular malformations in a specialist center of vascular anomalies in the UK over two years. RESULTS: Patients with vascular malformations reported significantly poorer SF-36 scores in all domains compared to the UK general population. Patients with low-flow vascular malformations, and arteriovenous malformations reported little variations in SF-36, HADS and VAS-P scores. No significant association was found between age, and any of the HRQoL scores other than the physical functioning in SF-36. Female patients reported significantly lower physical and social functioning of SF-36, and worse HADS-Depression than their male counterparts. Patients with syndromic vascular malformations reported significantly lower SF-36 scores in role-physical, role-emotional and bodily pain than non-syndromic vascular malformations. CONCLUSIONS: This study concluded that patients with vascular malformations reported worse QoL than the UK general population. Therefore, the assessment and management of QoL and mental health should be incorporated into the overall treatment strategies of patients with vascular malformations.
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Div of Surgery & Interventional Sci
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Department of Surgical Biotechnology
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