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Publication Detail
Integrated multi-modality image-guided navigation for neurosurgery: open-source software platform using state-of-the-art clinical hardware.
  • Publication Type:
    Journal article
  • Publication Sub Type:
  • Authors:
    Shapey J, Dowrick T, Delaunay R, Mackle EC, Thompson S, Janatka M, Guichard R, Georgoulas A, Pérez-Suárez D, Bradford R, Saeed SR, Ourselin S, Clarkson MJ, Vercauteren T
  • Publication date:
  • Journal:
    International Journal of Computer Assisted Radiology and Surgery
  • Status:
    Published online
  • Country:
  • PII:
  • Language:
  • Keywords:
    Computer-assisted interventions, Image-guided surgery, Intraoperative neuromonitoring, Intraoperative ultrasound, Neurosurgery, Open source
PURPOSE: Image-guided surgery (IGS) is an integral part of modern neuro-oncology surgery. Navigated ultrasound provides the surgeon with reconstructed views of ultrasound data, but no commercial system presently permits its integration with other essential non-imaging-based intraoperative monitoring modalities such as intraoperative neuromonitoring. Such a system would be particularly useful in skull base neurosurgery. METHODS: We established functional and technical requirements of an integrated multi-modality IGS system tailored for skull base surgery with the ability to incorporate: (1) preoperative MRI data and associated 3D volume reconstructions, (2) real-time intraoperative neurophysiological data and (3) live reconstructed 3D ultrasound. We created an open-source software platform to integrate with readily available commercial hardware. We tested the accuracy of the system's ultrasound navigation and reconstruction using a polyvinyl alcohol phantom model and simulated the use of the complete navigation system in a clinical operating room using a patient-specific phantom model. RESULTS: Experimental validation of the system's navigated ultrasound component demonstrated accuracy of [Formula: see text] and a frame rate of 25 frames per second. Clinical simulation confirmed that system assembly was straightforward, could be achieved in a clinically acceptable time of [Formula: see text] and performed with a clinically acceptable level of accuracy. CONCLUSION: We present an integrated open-source research platform for multi-modality IGS. The present prototype system was tailored for neurosurgery and met all minimum design requirements focused on skull base surgery. Future work aims to optimise the system further by addressing the remaining target requirements.
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Dept of Med Phys & Biomedical Eng
Dept of Med Phys & Biomedical Eng
Dept of Med Phys & Biomedical Eng
ARC Research Software Development Group
Dept of Computer Science
ARC Research Software Development Group
Dept of Med Phys & Biomedical Eng
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