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Publication Detail
An integrated bidirectional multi-channel opto-electro arbitrary waveform stimulator for treating motor neurone disease
  • Publication Type:
    Conference
  • Authors:
    Jiang D, Wu Y, Almarri N, Habibollahi M, Liu F, Bryson JB, Greensmith L, Demosthenous A
  • Publisher:
    IEEE
  • Publication date:
    27/04/2021
  • Published proceedings:
    Proceedings - IEEE International Symposium on Circuits and Systems
  • Volume:
    2021-May
  • ISBN-13:
    9781728192017
  • Status:
    Published
  • Name of conference:
    2021 IEEE International Symposium on Circuits and Systems (ISCAS)
  • Print ISSN:
    2158-1525
Abstract
This paper presents a prototype integrated bidirectional stimulator ASIC capable of mixed opto-electro stimulation and electrophysiological signal recording. The development is part of the research into a fully implantable device for treating motor neurone disease using optogenetics and stem cell technology. The ASIC consists of 4 stimulator units, each featuring 16-channel optical and electrical stimulation using arbitrary current waveforms with an amplitude up to 16 mA and a frequency from 1.5 Hz to 50 kHz, and a recording front-end with a programmable bandwidth of 1 Hz to 4 kHz, and a programmable amplifier gain up to 74 dB. The ASIC was implemented in a 0.18-┬Ám CMOS technology. Simulated performance in stimulation and recording is presented.
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Dept of Electronic & Electrical Eng
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Dept of Electronic & Electrical Eng
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Department of Neuromuscular Diseases
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Dept of Med Phys & Biomedical Eng
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Dept of Electronic & Electrical Eng
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Dept of Electronic & Electrical Eng
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Dept of Electronic & Electrical Eng
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