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Publication Detail
Rheumatic diseases and malignancy--is there an association?
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Article
  • Authors:
    Leandro MJ, Isenberg DA
  • Publication date:
    2001
  • Pagination:
    185, 188
  • Journal:
    Scandinavian Journal of Rheumatology
  • Volume:
    30
  • Issue:
    4
  • Print ISSN:
    0300-9742
  • Keywords:
    Arthritis, Association, ASSOCIATIONS, autoimmune, Autoimmune Diseases, cancer, complications, context, Dermatomyositis, developing, disease, Diseases, editorial, Epidemiologic Studies, Fibrosis, IM, INCREASED RISK, LA, Lung Neoplasms, Lupus, Lymphoma, Non-Hodgkin, MALIGNANCIES, Malignancy, Malignant, MALIGNANT DISEASE, May, Neoplasms, Paraneoplastic Syndromes, Patient, patients, PUBLISHED, pulmonary, Pulmonary Fibrosis, Review, REVIEWS, rheumatic disease, Rheumatic Diseases, Rheumatoid arthritis, RHEUMATOID-ARTHRITIS, Risk, Risk Factors, risks, Scleroderma, Systemic, SCLEROSIS, Setting, SETTINGS, Sjogren's Syndrome, Syndrome, SYSTEMIC, SYSTEMIC LUPUS ERYTHEMATOSUS, SYSTEMIC SCLEROSIS, SYSTEMIC-LUPUS-ERYTHEMATOSUS, SYSTEMIC-SCLEROSIS, THERAPIES, therapy
  • Notes:
    UI - 21461755 LA - eng PT - Editorial PT - Review PT - Review, Tutorial DA - 20011001 IS - 0300-9742 SB - IM CY - Norway
Abstract
An association between rheumatic diseases and malignancy has been claimed in a variety of settings. This editorial reviews published data addressing the overall risk of malignancy, and of particular types of cancer, in the context of various autoimmune rheumatic diseases. For patients with Sjogren's syndrome, systemic sclerosis with pulmonary fibrosis, or with dermatomyositis/polymyositis there is a documented association with an increased risk of malignant disease. Patients with rheumatoid arthritis may also have an increased risk of cancer. It is still controversial whether systemic lupus erythematosus is associated with an increased risk of developing malignancy. More epidemiologic studies are needed to try and clarify many of these associations, in particular the potential risks associated with cytotoxic therapy
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