Whilst there is a current tendency in the social sciences on the subject of sex and gender to privilege similarities over differences (e.g. Hyde, 2005), there is also significant evidence that sex/gender differences do play a role in mental health outcomes as in many other spheres of life (Tamres et al., 2002). However, such differences are not emphasised in the training of psychological practitioners and therapists, which means that the needs of male clients might not be met (Morison et al., 2014; Barry et al., 2021). Whilst respecting sex/gender differences, it is of course important to recognise that these constitute averages, and that individuals within any category vary on a spectrum. No individual therefore is defined by their sex or gender. All psychological interventions must above all tune in to the unique individual world of the client, without prejudging a person based on any identity category. The following is simply to provide more detail and information for psychological practitioners about the gendered aspects of men’s lives so as to enrich and improve their formulations and interventions. These guidelines are not therefore prescriptive, ‘one size fits all’ or based on simplistic generalisations or stereotypes about men and boys. Their purpose is to enrich and widen psychological practice with respect for sex and gender as one of many interacting variables.