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Publication Detail
Progress in applications of magnetic nanoparticles in biomedicine
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Article
  • Authors:
    Pankhurst QA, Thanh NTK, Jones SK, Dobson J
  • Publication date:
    2009
  • Journal:
    JOURNAL OF PHYSICS D-APPLIED PHYSICS
  • Volume:
    42
  • Article number:
    22
  • Status:
    Published
  • Print ISSN:
    0022-3727
  • Notes:
    article-number: 224001 unique-id: ISI:000271519000005
Abstract
A progress report is presented on a selection of scientific, technological and commercial advances in the biomedical applications of magnetic nanoparticles since 2003. Particular attention is paid to (i) magnetic actuation for in vitro non-viral transfection and tissue engineering and in vivo drug delivery and gene therapy, (ii) recent clinical results for magnetic hyperthermia treatments of brain and prostate cancer via direct injection, and continuing efforts to develop new agents suitable for targeted hyperthermia following intravenous injection and (iii) developments in medical sensing technologies involving a new generation of magnetic resonance imaging contrast agents, and the invention of magnetic particle imaging as a new modality. Ongoing prospects are also discussed.
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