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Publication Detail
A spatial variation model of white matter microstructure
  • Publication Type:
    Conference presentation
  • Authors:
    Morgan GL, Zhang H, Whitcher B, Alexander DC
  • Date:
  • Status:
  • Name of Conference:
    CDMRI'10: MICCAI 2010 Workshop on Computational Diffusion MRI
  • Conference place:
    Beijing, China
  • Conference start date:
  • Conference finish date:
In this study, we introduce a new technique to model the variation of microstructural parameters across speci c brain regions. We use a simple model of di usion in each voxel, but model the variation of parameters across the region using penalised splines. We t the whole region model directly to the di usion-weighted signals. We test the tech- nique on the mid-sagittal section of the corpus callosum (CC) using a di usion MRI data set with distinct age groups. The method detects di erences and separates the groups.
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