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Publication Detail
Rapid flow assessment of congenital heart disease using high spatio-temporal gated spiral phase contrast MR
  • Publication Type:
    Journal article
  • Publication Sub Type:
  • Authors:
    Steeden JA, ATKINSON D, Hansen MS, Taylor AM, Muthurangu V
  • Publication date:
  • Pagination:
    79, 87
  • Journal:
  • Volume:
  • Issue:
  • Status:
Purpose: The aim of this paper was to compare flow volumes and image quality measured using: a) reference free-breathing, retrospectively cardiac-gated, Cartesian,bphase-contract magnetic resonance imaging (PCMR), b) standard breath-hold, retrospectively cardiac-gated, Cartesian, PCMR, and c) prospectively cardiac-triggered, spiral, sensitivity encoding(SENSE), breath-hold PCMR. Materials and Methods: The local research ethics committee approved this study and written consent was obtained from all patients. Stroke volume, regurgitation fraction, Qp/Qs and RPA/LPA ratios were quantified using the three sequences from 40 patients with congenital heart disease. These functional parameters were compared using repeatedmeasures ANOVA tests, Bland-Altman analysis and correlation coefficients. Signal-tonoise ratio (SNR), velocity-to-noise ratio (VNR) and edge sharpness were also compared using repeated-measures ANOVA tests. Results: Scan time was significantly reduced for the breath-hold spiral PCMR sequence, compared to the standard breath-hold PCMR sequence (~5 vs. ~18 seconds, respectively). There was an excellent agreement in stroke volume, QP/QS and RPA/LPA ratios between all sequences, however the spiral breath-hold sequence was found to be superior to the standard breath-hold sequence in terms of limits of agreement and correlation. There was a small but statistically significant underestimation of regurgitation fraction using the spiral sequence. SNR and VNR were lower for the spiral breath-hold sequence compared with the standard breath-hold sequence, however the edge sharpness was greater for the spiral breath-hold sequence. Conclusion: Flow volumes can be accurately and reliably quantified using a spiral SENSE PCMR sequence, with high spatio-temporal resolution in a short breath-hold.
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