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Publication Detail
A new validation method for establishing correspondence between pairs of X-ray mammograms
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Conference Proceeding
  • Authors:
    Hipwell JH, Tanner C, Crum WR, Hawkes DJ
  • Publication date:
  • Journal:
    Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition
  • Volume:
  • Status:
  • Print ISSN:
Establishing spatial correspondence between features visible in x-ray mammograms obtained at different times has great potential to aid assessment of change in the breast indicative of malignant changes and facilitate their quantification. The literature contains numerous non-rigid registration algorithms developed for this purpose, but quantitative estimation of registration accuracy is limited. In this paper we describe a novel validation method which simulates plausible mammographic compressions of the breast using an MRI derived finite element model. By projecting the resulting known 3D displacements into 2D and simulating x-ray mammograms from these same compressed MR volumes, we can generate convincing images with known 2D displacements with which to validate a registration algorithm. We illustrate this approach by computing the accuracy for a non-rigid registration algorithm applied to mammographie test images generated from three patient MR datasets. © 2006 IEEE.
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