UCL  IRIS
Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
Publication Detail
Perinatal gene delivery to the CNS
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Review
  • Authors:
    Rahim AA, Buckley SMK, Chan JKY, Peebles DM, Waddington SN
  • Publication date:
    01/04/2011
  • Pagination:
    483, 491
  • Journal:
    Therapeutic Delivery
  • Volume:
    2
  • Issue:
    4
  • Status:
    Published
  • Print ISSN:
    2041-5990
Abstract
The relative inaccessibility of the brain compared with other major organs, the highly regulated transfer of molecules across the blood-brain barrier and the limited capacity of neurons to regenerate, make efficient gene delivery to the CNS both challenging and imperative. Perinatal gene delivery to the CNS represents a powerful tool for the investigation of genes in development and disease. However, it may also hold immense therapeutic value for neonatal lethal neurodegenerative diseases for which no treatment is available. This article will focus on the use of perinatal gene delivery as a research tool and the potential it has to develop into a realistic therapy that can be translated to the clinic. © 2011 Future Science Ltd.
Publication data is maintained in RPS. Visit https://rps.ucl.ac.uk
 More search options
UCL Researchers Show More
Author
Maternal & Fetal Medicine
Author
Maternal & Fetal Medicine
Author
Pharmacology
Author
Maternal & Fetal Medicine
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by