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Publication Detail
Might makes right: Using force to align the mitotic spindle.
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Comment
  • Authors:
    Lancaster OM, Baum B
  • Publication date:
    07/2011
  • Pagination:
    736, 738
  • Journal:
    Nat Cell Biol
  • Volume:
    13
  • Issue:
    7
  • Country:
    England
  • PII:
    ncb0711-736
  • Language:
    eng
  • Keywords:
    Actins, Animals, Cell Adhesion, Cell Polarity, Cell Shape, Fibronectins, Homeostasis, Humans, Mechanotransduction, Cellular, Mitosis, Morphogenesis, Rotation, Spindle Apparatus, Stress, Mechanical
Abstract
Both symmetric and asymmetric divisions rely on alignment of the mitotic spindle with cues from the environment. A study now shows that mitotic spindles find their position by reading the map of forces that load-bearing retraction fibres exert on the cell body.
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