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Publication Detail
Collagen imaged by Coherent X-ray Diffraction: towards a complementary tool to conventional scanning SAXS
  • Publication Type:
    Conference
  • Authors:
    Berenguer de la Cuesta F, Bean RJ, McCallion C, Wallace K, Bozec L, Hiller JC, Terrill NJ, Robinson IK
  • Publisher:
    IOP PUBLISHING LTD
  • Publication date:
    2010
  • Published proceedings:
    XIV INTERNATIONAL CONFERENCE ON SMALL-ANGLE SCATTERING (SAS09)
  • Volume:
    247
  • Editors:
    Ungar G
  • Name of conference:
    14th International Conference on Small-Angle Scattering (SAS09)
  • Conference place:
    Oxford, ENGLAND
  • Conference start date:
    13/09/2009
  • Conference finish date:
    18/09/2009
  • Print ISSN:
    1742-6588
  • Language:
    EN
  • Keywords:
    PHASE RETRIEVAL, SCATTERING, RESOLUTION, BONE, MICROSCOPY, ALGORITHM, FIBRILS, DEFORMATION, PACKING, CORNEA
Abstract
Third generation x-ray sources offer unique possibilities for exploiting coherence in the study of materials. New insights in the structure and dynamics of soft condensed matter and biological samples can be obtained by coherent x-ray diffraction (CXD). However, the experimental procedures for applying these methods to collagen tissues are still under development. We present here an investigation for the optimal procedure in order to obtain high quality CXD data from collagen tissues. Sample handling and preparation and adequate coherence defining apertures are among the more relevant factors to take into account. The impact of the results is also discussed, in particular in comparison with the information that can be extracted from conventional scanning small angle x-ray scattering (SAXS). Images of collagen tissues obtained by CXD reconstructions will give additional information about the local structure with higher resolution and will complement scanning SAXS images.
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