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Publication Detail
Periodontal healing following avulsion and replantation of teeth: a multi-centre randomized controlled trial to compare two root canal medicaments.
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Comparative Study
  • Authors:
    Day PF, Gregg TA, Ashley P, Welbury RR, Cole BO, High AS, Duggal MS
  • Publication date:
  • Pagination:
    55, 64
  • Journal:
    Dent Traumatol
  • Volume:
  • Issue:
  • Status:
  • Country:
  • Language:
  • Keywords:
    Adolescent, Calcium Hydroxide, Child, Demeclocycline, Drug Combinations, Female, Follow-Up Studies, Humans, Male, Periodontal Ligament, Root Canal Irrigants, Root Canal Therapy, Root Resorption, Single-Blind Method, Tooth Ankylosis, Tooth Avulsion, Tooth Replantation, Treatment Outcome, Triamcinolone Acetonide, Wound Healing
BACKGROUND:  Non-setting calcium hydroxide (Ultracal XS(®) ) is recommended by the International Association of Dental Traumatology as the initial medicament following avulsion and replantation for mature teeth. There is experimental evidence to suggest Ledermix(®) , placed as an alternative inter-visit dressing may improve periodontal healing. AIM:  This study investigated, using a multi-centre randomized controlled trial, the effect of two root canal medicaments, Ledermix(®) and Ultracal XS(®) , on periodontal healing of avulsed and replanted teeth. MATERIAL AND METHODS:  Children were recruited if they fulfilled all inclusion criteria. Treatment followed a standardized protocol. Assessment of periodontal healing or ankylosis was made clinically and radiographically by an experienced, 'blinded', clinician at 12months. RESULTS:  Over 200 patients were assessed for eligibility at five centres. Twenty-nine patients were eligible for inclusion. Final analysis involved 22 patients with 27 teeth. Ankylosis was detected in four of the 12 teeth in the Ledermix(®) group and nine of 15 in the Ultracal XS(®) group. No significant difference between medicaments was found in the proportion of teeth or patients showing periodontal healing. DISCUSSION:  There was no significant difference in periodontal healing between the two medicaments at either a tooth or patient level. The numbers recruited fell short of an estimated power calculation. For patients meeting the inclusion criteria and completing the trial, periodontal healing was seen in 52% of teeth at the 12-month assessment between both groups. The only factor found to significantly influence the periodontal outcome was dry time.
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