UCL  IRIS
Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data shown on the profile page to:

http://www.ucl.ac.uk/finance/secure/research/post_award
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
Publication Detail
In vitro assessment of shiitake mushroom (Lentinula edodes) extract for its antigingivitis activity.
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Journal Article
  • Authors:
    Ciric L, Tymon A, Zaura E, Lingström P, Stauder M, Papetti A, Signoretto C, Pratten J, Wilson M, Spratt D
  • Publication date:
    2011
  • Pagination:
    507908, ?
  • Journal:
    J Biomed Biotechnol
  • Volume:
    2011
  • Country:
    United States
  • Language:
    eng
  • Keywords:
    Analysis of Variance, Anti-Infective Agents, Bacteria, Biofilms, Chlorhexidine, Gingivitis, Humans, Microbiological Techniques, Saliva, Shiitake Mushrooms
  • Notes:
    PMCID: PMC3182071
Abstract
Gingivitis is a preventable disease characterised by inflammation of the gums due to the buildup of a microbial biofilm at the gingival margin. It is implicated as a precursor to periodontitis, a much more serious problem which includes associated bone loss. Unfortunately, due to poor oral hygiene among the general population, gingivitis is prevalent and results in high treatment costs. Consequently, the option of treating gingivitis using functional foods, which promote oral health, is an attractive one. Medicinal mushrooms, including shiitake, have long been known for their immune system boosting as well as antimicrobial effects; however, they have not been employed in the treatment of oral disease. In the current study, the effectiveness of shiitake mushroom extract was compared to that of the active component in the leading gingivitis mouthwash, containing chlorhexidine, in an artificial mouth model (constant depth film fermenter). The total bacterial numbers as well as numbers of eight key taxa in the oral community were investigated over time using multiplex qPCR. The results indicated that shiitake mushroom extract lowered the numbers of some pathogenic taxa without affecting the taxa associated with health, unlike chlorhexidine which has a limited effect on all taxa.
Publication data is maintained in RPS. Visit https://rps.ucl.ac.uk
 More search options
UCL Authors Show More
Dept of Civil, Environ & Geomatic Eng
Eastman Dental Institute
Microbial Diseases
Microbial Diseases
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by