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Publication Detail
Automated DNA Motif Discovery
  • Publication Type:
    Other
  • Authors:
    Langdon WB, Graillet OS, Harrison AP
  • Publication date:
    30/01/2010
  • Medium:
    arXiv
  • Notes:
    keywords: genetic algorithms, genetic programming, pseudogene, short and microRNAs, non-coding transcripts, systems biology, machine learning, Bioinformatics, motif, regular expression, strongly typed genetic programming, context-free grammar size: 12 pages
Abstract
Ensembl’s human non-coding and protein coding genes are used to automatically find DNA pattern motifs. The Backus-Naur form (BNF) grammar for regular expressions (RE) is used by genetic programming to ensure the generated strings are legal. The evolved motif suggests the presence of Thymine followed by one or more Adenines etc. early in transcripts indicate a non-protein coding gene.
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