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Publication Detail
High Resolution Slice-Selective Fourier Velocity encoding in congenital heart disease using spiral SENSE with velocity unwrap
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Article
  • Authors:
    Steeden JA, Jones A, Pandya B, Atkinson D, Taylor AM, Muthurangu V
  • Publication date:
    06/2012
  • Pagination:
    1538, 1546
  • Journal:
    Magnetic Resonance in Medicine
  • Volume:
    67
  • Issue:
    6
  • Status:
    Published
  • Keywords:
    Fourier Velocity Encoding, Peak Velocity, Congenital Heart Disease
Abstract
Quantification of peak velocity is important in the assessment of stenotic flow jets in patients with congenital heart disease (CHD). Phase contrast magnetic resonance (PCMR) underestimates peak velocities, hence clinically Doppler ultrasound (US) is used as the reference standard for assessing stenoses. It is possible to measure peak velocity accurately in MR using Fourier Velocity Encoding (FVE). In this study, a fast, high-resolution slice-selective FVE sequence was developed with the use of spiral trajectories, parallel-imaging, partial-Fourier in the velocity dimension and a novel velocity-unwrap technique. The resulting sequence was acquired within a short breath-hold (over 15 heartbeats) making this FVE technique clinically achievable. Peak velocities were compared from Doppler US, PCMR and FVE. Experiments were carried out in-vitro and in-vivo in 25 CHD patients with stenoses. It was shown that in-vitro and in-vivo PCMR tended to underestimate peak velocity compared to Doppler US, whereas FVE agreed well with Doppler US.
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Metabolism & Experi Therapeutics
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Children's Cardiovascular Disease
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Children's Cardiovascular Disease
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Children's Cardiovascular Disease
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