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Publication Detail
MRI derived small bowel motility as a marker of Crohn’s disease activity
  • Publication Type:
  • Authors:
    Menys A, Odille F, Punwani S, Novelli M, Rodriguez-Justo M, Halligan S, Atkinson D, Taylor S
  • Publication date:
  • Pagination:
    1274, ?
  • Status:
  • Name of conference:
    ISMRM 2012
  • Conference place:
    Melbourne, Australia
  • Conference start date:
  • Conference finish date:
Optimal medical management of Crohn’s disease (CD) relies on accurate identification of patients with acute inflammation. Currently a number of anatomical features seen on MR enterography have been shown to correlate closely with disease activity. Abnormal intestinal motility has been described in CD and may also be a marker for disease activity. We explored quantitatively the relationship between CD activity and intestinal motility assessed using MRI (n=23) against a histopathological standard of reference and validated anatomical MRI markers of activity. We found significant relationships between motility and both end points suggesting motility as a biomarker for inflammatory activity.
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