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Publication Detail
Quantitative spectroscopic photoacoustic imaging: a review.
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Journal Article
  • Authors:
    Cox B, Laufer JG, Arridge SR, Beard PC
  • Publication date:
    06/2012
  • Pagination:
    061202, ?
  • Journal:
    J Biomed Opt
  • Volume:
    17
  • Issue:
    6
  • Status:
    Published
  • Country:
    United States
  • Language:
    eng
  • Keywords:
    Acoustics, Algorithms, Animals, Diagnostic Imaging, Humans, Light, Microscopy, Acoustic, Models, Statistical, Molecular Imaging, Monte Carlo Method, Optics and Photonics, Oxygen, Photoacoustic Techniques, Reproducibility of Results, Scattering, Radiation, Spectrum Analysis
Abstract
Obtaining absolute chromophore concentrations from photoacoustic images obtained at multiple wavelengths is a nontrivial aspect of photoacoustic imaging but is essential for accurate functional and molecular imaging. This topic, known as quantitative photoacoustic imaging, is reviewed here. The inverse problems involved are described, their nature (nonlinear and ill-posed) is discussed, proposed solution techniques and their limitations are explained, and the remaining unsolved challenges are introduced.
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