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Publication Detail
The metastatic cancer cell cortex: an adaptation to enhance robust cell division in novel environments?
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Journal Article
  • Authors:
    Matthews HK, Baum B
  • Publication date:
  • Pagination:
    1017, 1020
  • Journal:
  • Volume:
  • Issue:
  • Status:
  • Country:
    United States
  • Language:
  • Keywords:
    Actins, Adaptation, Physiological, Animals, Cell Division, Cytoskeletal Proteins, Humans, Membrane Proteins, Mitosis, Neoplasm Metastasis, Neoplasms, Oncogenes, Proto-Oncogene Proteins
To metastasize, cancer cells must be able to complete cell division in environments very different from their tissue of origin. We suggest that mitotic cell rounding, aided by several actin-regulatory oncogenes, may facilitate this process in a robust, context-independent manner.
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