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Publication Detail
Comparison and evaluation of rigid, affine, and nonrigid registration of breast MR images
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Article
  • Authors:
    Denton ER, Sonoda LI, Rueckert D, Rankin SC, Hayes C, Leach MO, Hill DL, Hawkes DJ
  • Publication date:
    09/1999
  • Pagination:
    800, 805
  • Journal:
    J COMPUT ASSIST TOMOGR
  • Volume:
    23
  • Issue:
    363-8715 (Print), 5
  • Keywords:
    Adult, Aged, Algorithms, Breast, pathology, Comparative Study, Contrast Media, Female, Gadolinium DTPA, diagnostic use, Humans, Magnetic Resonance Imaging, instrumentation, methods, statistics & numerical data, Middle Aged, Observer Variation, Research Support, Non-U.S.Gov't, Statistics, Nonparametric
  • Addresses:
    Department of Radiology, King's College Hospital, London, England
  • Notes:
    DA - 19991027
Abstract
PURPOSE: A new nonrigid registration method, designed to reduce the effect of movement artifact in subtraction images from breast MR, is compared with existing rigid and affine registration methods. METHOD: Nonrigid registration was compared with rigid and affine registration methods and unregistered images using 54 gadolinium-enhanced 3D breast MR data sets. Twenty-seven data sets had been previously reported normal, and 27 contained a histologically proven carcinoma. The comparison was based on visual assessment and ranking by two radiologists. RESULTS: When analyzed by two radiologists independently, all three registration methods gave better-quality subtraction images than unregistered images (p < 0.01), but nonrigid registration gave significantly better results than the rigid and affine registration methods (p < 0.01). There was no significant difference between rigid and affine registration methods. CONCLUSION: Nonrigid registration significantly reduces the effects of movement artifact in subtracted contrast-enhanced breast MRI. This may enable better visualization of small tumors and those within a glandular breast
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Dept of Med Phys & Biomedical Eng
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