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Publication Detail
Modification of the release characteristics of estradiol encapsulated in PLGA particles via surface coating.
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Journal Article
  • Authors:
    Enayati M, Stride E, Edirisinghe M, Bonfield W
  • Publication date:
  • Pagination:
    209, 226
  • Journal:
    Ther Deliv
  • Volume:
  • Issue:
  • Country:
  • Print ISSN:
  • Language:
  • Keywords:
    Chemistry, Pharmaceutical, Chitosan, Coated Materials, Biocompatible, Delayed-Action Preparations, Drug Carriers, Drug Compounding, Estradiol, Gelatin, Kinetics, Lactic Acid, Nanoparticles, Particle Size, Polyglycolic Acid, Solubility, Surface Properties, Technology, Pharmaceutical
Drug-loaded poly(lactide-co-glycolide) particles (100-4500 nm in diameter) were prepared via the electrospraying method. An extensive study was then carried out to determine the parameters affecting the release profile of estradiol (the drug or active pharmaceutical ingredient) in order to facilitate minimum initial burst release of estradiol.
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