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Publication Detail
Vector systems for prenatal gene therapy: choosing vectors for different applications.
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Journal Article
  • Authors:
    Coutelle C, Waddington SN
  • Publication date:
    2012
  • Pagination:
    41, 53
  • Journal:
    Methods Mol Biol
  • Volume:
    891
  • Status:
    Published
  • Country:
    United States
  • Language:
    eng
  • Keywords:
    Animals, Gene Expression, Genetic Diseases, Inborn, Genetic Therapy, Genetic Vectors, Humans, Prenatal Care
Abstract
This chapter gives a comparative review of the different vector systems applied to date in prenatal gene therapy experiments highlighting the need for versatility and choice for application in accordance with the actual aim of the study. It reviews the key characteristics of the four main gene therapy vector systems and gives examples for their successful application in prenatal gene therapy experiments.
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