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Publication Detail
CSF-filtration: An experimental therapeutical approach in multiple sclerosis treatment
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Conference Proceeding
  • Authors:
    Haas J, Sailer M, Duzel E, Tendolkar I, Wurster U
  • Publication date:
  • Pagination:
    109, 111
  • Journal:
  • Volume:
  • Issue:
  • Status:
  • Print ISSN:
Despite new innovative immunomodulating therapeutical approaches in multiple sclerosis there is no promising treatment for patients with long-standing disease and severe disability. The plasmapheresis was used in open and controlled trials in some cases with acute or fulminant course of the disease. In analogy to this treatment the CSF-filtration comprises a new therapeutical approach. We conducted a pilot-study treating 10 patients with MS with a long-standing or severely disabling disease. In 3 patients we found a marked and in 3 patients a moderate improvement of the clinical symptoms. The CSF-filtration was well tolerated, adverse events or complications were not observed. At this point of time we regard CSF-filtration as an experimental therapy which has to be evaluated for its efficacy and safety in MS and other diseases.
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