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Publication Detail
The regulation of cell size.
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Journal Article
  • Authors:
    Lloyd AC
  • Publication date:
    12/09/2013
  • Pagination:
    1194, 1205
  • Journal:
    Cell
  • Volume:
    154
  • Issue:
    6
  • Status:
    Published
  • Country:
    United States
  • PII:
    S0092-8674(13)01084-2
  • Language:
    eng
  • Keywords:
    Animals, Cell Cycle, Cell Proliferation, Cell Size, Homeostasis, Humans, Neoplasms, Organ Size, Signal Transduction
Abstract
An adult animal consists of cells of vastly different size and activity, but the regulation of cell size remains poorly understood. Recent studies uncovering some of the signaling pathways important for size/growth control, together with the identification of diseases resulting from aberrations in these pathways, have renewed interest in this field. This Review will discuss our current understanding of how a cell sets its size, how it can adapt its size to a changing environment, and how these processes are relevant to human disease.
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