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Publication Detail
Framework for the construction of a Monte Carlo simulated brain PET-MR image database
  • Publication Type:
    Journal article
  • Authors:
    Thomas BA, Erlandsson K, Bousse A, Hutton BF, Drobnjak I, Pedemonte S, Ourselin S, Vunckx K, Reilhac-Laborde A
  • Publication date:
    2013
  • Journal:
    Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
  • Print ISSN:
    0168-9002
Abstract
Simultaneous PET-MR acquisition reduces the possibility of registration mismatch between the two modalities. This facilitates the application of techniques, either during reconstruction or post-reconstruction, that aim to improve the PET resolution by utilising structural information provided by MR. However, in order to validate such methods for brain PET-MR studies it is desirable to evaluate the performance using data where the ground truth is known. In this work, we present a framework for the production of datasets where simulations of both the PET and MR, based on real data, are generated such that reconstruction and post-reconstruction approaches can be fairly compared. © 2013 Elsevier B.V. All rights reserved.
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