Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at http://www.ucl.ac.uk/finance/research/post_award/post_award_contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
Publication Detail
Boron-doped nanocrystalline diamond microelectrode arrays monitor cardiac action potentials
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Journal Article
  • Authors:
    Maybeck V, Edgington R, Bongrain A, Welch JO, Scorsone E, Bergonzo P, Jackman RB, Offenhäusser A
  • Publication date:
  • Pagination:
    283, 289
  • Journal:
    Advanced Healthcare Materials
  • Volume:
  • Issue:
  • Print ISSN:
  • Language:
  • Keywords:
    Action potential, Diamond microelectrode array, Nanocrystalline diamond
The expansion of diamond-based electronics in the area of biological interfacing has not been as thoroughly explored as applications in electrochemical sensing. However, the biocompatibility of diamond, large safe electrochemical window, stability, and tunable electronic properties provide opportunities to develop new devices for interfacing with electrogenic cells. Here, the fabrication of microelectrode arrays (MEAs) with boron-doped nanocrystalline diamond (BNCD) electrodes and their interfacing with cardiomyocyte-like HL-1 cells to detect cardiac action potentials are presented. A nonreductive means of structuring doped and undoped diamond on the same substrate is shown. The resulting BNCD electrodes show high stability under mechanical stress generated by the cells. It is shown that by fabricating the entire surface of the MEA with NCD, in patterns of conductive doped, and isolating undoped regions, signal detection may be improved up to four-fold over BNCD electrodes passivated with traditional Isolators. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication data is maintained in RPS. Visit https://rps.ucl.ac.uk
 More search options
UCL Researchers
Dept of Electronic & Electrical Eng
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by