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Publication Detail
Multi-modal pharmacokinetic modelling for DCE-MRI: using diffusion weighted imaging to constrain the local arterial input function
  • Publication Type:
    Conference
  • Authors:
    Hamy V, Modat M, Dikaios N, Cleary J, Punwani S, Shipley R, Ourselin S, Atkinson D, Melbourne A
  • Publication date:
    15/02/2014
  • Pagination:
    9034-26, ?
  • Status:
    Published
  • Name of conference:
    SPIE Medical Imaging 2014
  • Conference place:
    San Diego, California, United States
  • Conference start date:
    15/02/2014
  • Conference finish date:
    20/02/2014
Abstract
In this work we hypothesise that diffusion weighted imaging data may help constrain the fitting of pharmacokinetic models to dynamic contrast enhanced (DCE) MRI data. Parameters related to tissue perfusion in the intra-voxel incoherent motion (IVIM) modelling of diffusion weighted MRI provide local information on how tissue is likely to perfuse that can be utilised to guide DCE modelling via local modification of the arterial input function (AIF).
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