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Publication Detail
Neurite orientation dispersion and density imaging of the cervical cord in vivo
  • Publication Type:
    Conference presentation
  • Authors:
    Grussu F, Schneider T, Zhang H, Alexander DC, Wheeler-Kingshott CAM
  • Date:
  • Status:
  • Name of Conference:
    Joint Annual Meeting ISMRM-ESMRMB
  • Conference place:
    Milan, Italy
  • Conference start date:
  • Conference finish date:
  • Keywords:
    NODDI, spinal cord, DTI, in vivo, microstructure, orientation dispersion, neurite morphology
Neurite Orientation Dispersion and Density Imaging (NODDI) is a novel diffusion MRI technique providing indices which are appealing biomarkers in diseases of brain and spinal cord. Here, we demonstrate for the first time the application of the full NODDI technique to the healthy cervical cord in vivo, assessing the reproducibility of its metrics and their relationship with Diffusion Tensor Imaging (DTI) indices. The analysis confirmed findings in the brain and demonstrated that NODDI can be a feasible and more specific alternative to DTI for in vivo spinal cord diffusion MRI.
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