Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
Publication Detail
Functional representation of living and nonliving domains across the cerebral hemispheres: A combined ERP/TMS study
  • Publication Type:
    Journal article
  • Publication Sub Type:
  • Authors:
    Fuggetta G, Rizzo S, Pobric G, Lavidor M, Walsh V
  • Journal:
    Journal of Cognitive Neuroscience
  • Status:
  • Print ISSN:
Transcranial magnetic stimulation (TMS) over the left hemisphere has been shown to disrupt semantic processing but to date there has been no direct demonstration of the electrophysiological correlates of this interference. To gain insight into the neural basis of semantic systems, and in particular study the temporal and functional organization of object categorization processing, we combined repetitive TMS (rTMS) and event-related potentials (ERPs). Healthy volunteers performed a picture-word matching task in which Snodgrass drawings of natural (e.g. animal) and artifactual (e.g. tool) categories were associated with a word. When short trains of high-frequency rTMS were applied over Wernicke's area (in the region of the CP5 electrode) immediately before the stimulus onset, we observed delayed response times to artifactual items, and thus an increased dissociation between natural and artifactual domains. This behavioural effect had a direct ERP correlate. In the response period, the stimuli from the natural domain elicited a significant larger late positivity complex (LPC) than those from the artifactual domain. These differences were significant over the centro-parietal region of the right hemisphere. These findings demonstrate that rTMS interferes with post-perceptual categorization processing of natural and artifactual stimuli that involve separate subsystems in remote cortical areas.
Publication data is maintained in RPS. Visit https://rps.ucl.ac.uk
 More search options
UCL Researchers
Institute of Cognitive Neuroscience
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by