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Publication Detail
Multiple Fibers. Beyond the Diffusion Tensor.
This chapter covers techniques for resolving multiple fiber populations in each voxel, as well as methods to exploit the information they recover. It begins by describing the limitations of diffusion tensor imaging and the problems that complex white matter configurations such as crossing-fiber populations and bending fibers present. It then goes on to describe multiple-tensor models, diffusion spectrum imaging, QBall, spherical deconvolution and persistent angular structure MRI, along with a summary of pros and cons of each method. The next section covers useful information that can be extracted from the output of the techniques presented, such as estimates of fiber orientations and indices of anisotropy and complexity. Finally, tractography methods for exploiting the multiple fiber reconstruction algorithms and their metrics are briefly discussed. © 2014 Elsevier Inc. All rights reserved.
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